High-fat meals rich in EPA plus DHA compared with DHA only have differential effects on postprandial lipemia and plasma 8-isoprostane F2a concentrations relative to a control high–oleic acid meal: a randomized controlled trial
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چکیده
Background: Eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) supplementation has beneficial cardiovascular effects, but postprandial influences of these individual fatty acids are
منابع مشابه
High-fat meals rich in EPA plus DHA compared with DHA only have differential effects on postprandial lipemia and plasma 8-isoprostane F2α concentrations relative to a control high–oleic acid meal: a randomized controlled trial1234
BACKGROUND Eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) supplementation has beneficial cardiovascular effects, but postprandial influences of these individual fatty acids are unclear. OBJECTIVES The primary objective was to determine the vascular effects of EPA + DHA compared with DHA only during postprandial lipemia relative to control high-oleic acid meals; the secondary obje...
متن کاملImpaired postprandial endothelial function depends on the type of fat consumed by healthy men.
Postprandial lipemia impairs endothelial function possibly via an oxidative stress mechanism. A stearic acid-rich triacylglycerol (TAG) (shea butter) results in a blunted postprandial increase in plasma TAG compared with an oleic acid-rich TAG; however, its acute effects on endothelial function and oxidative stress are unknown. A randomized crossover trial (n = 17 men) compared the effects of 5...
متن کاملAn impact on arterial stiffness and compliance, associ- ated with reduced blood pressure (1–4), is thought to be a significant contributor to the lower CVD risk associated with increased long chain n-3 PUFA (LC n-3 PUFA; EPA
This article is available online at http://www.jlr.org An impact on arterial stiffness and compliance, associated with reduced blood pressure (1–4), is thought to be a significant contributor to the lower CVD risk associated with increased long chain n-3 PUFA (LC n-3 PUFA; EPA plus DHA) intake and status (4–6). In randomized controlled trials (RCTs) conducted to date, vascular function is typic...
متن کاملPalmitic acid in the sn-2 position of triacylglycerols acutely influences postprandial lipid metabolism.
BACKGROUND The triacylglycerol structure of saturated fats may influence postprandial lipemia. OBJECTIVE We tested the hypothesis that high-fat meals rich in palmitic acid (16:0) in the sn-2 position decrease lipemia. DESIGN Postprandial changes in plasma lipids, apolipoprotein B48, and cytokines were compared in healthy men (n = 25) and women (n = 25) by using a randomized crossover design...
متن کاملLack of effect of meal fatty acid composition on postprandial lipid, glucose and insulin responses in men and women aged 50-65 years consuming their habitual diets.
The aim of the study was to determine the effect of consuming meals with different fatty acid compositions on the postprandial changes over 6 h in plasma triacylglycerol, NEFA, total cholesterol, glucose and insulin concentrations in middle-aged men and women. Men (n 11; 58 (5) years) and women (n 11; 56 (4) years) consumed four test meals with a similar macronutrient energy content in random o...
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